Result: During cap stage and early bell stage, the expression of MMP-20 mRNA was negative in enamel organ, dental papilla and dental sac and that of TIMP-1 mRNA could be observed in dental papilla; 结果:帽状期及钟状早期,成釉器、牙乳头及牙囊MMP-20mRNA表达阴性;TIMP-1mRNA在牙乳头表达;
BMP may also be found in human tooth germs, predentin, the cells of outer and inner enamel epithelium, and the cells of dental sac generating alveolar bone. 在人的牙胚中,BMP主要分布在前期牙木质、外釉细胞和造釉细胞以及形成牙槽骨的牙囊细胞中,表明骨的生长和形成以及牙齿的发育都与BMR密切相关。